Research Articles
JNJ-7706621 vs. Cytochalasin B: A New Paradigm for Enhancing SCNT Embryo Development and Cloning Efficiency
Somatic cell nuclear transfer (SCNT) is a pivotal technique for animal cloning and regenerative medicine, yet its efficiency remains low due to poor embryonic developmental competence.
Strain-Specific Maternal Care in Laboratory Mice: Impacts on Pup Survival and Practical Breeding Strategies
This article synthesizes current research on how maternal care differs across common laboratory mouse strains and its profound impact on pup survival and development.
Overcoming Light Penetration Barriers in Embryonic Optogenetics: A Comprehensive Troubleshooting Guide
This article addresses the critical challenge of limited tissue penetration in embryonic optogenetics, a significant bottleneck for researchers studying developmental processes.
Unlocking Single-Molecule Detection: How RNAscope's Sensitivity Surpasses Traditional ISH
This article provides a comprehensive analysis for researchers and drug development professionals on the significant advancements in in situ hybridization (ISH) sensitivity offered by RNAscope technology.
RNAscope vs. IHC: A Comprehensive Analysis of Sensitivity, Specificity, and Clinical Utility
This article provides a critical comparison between RNAscope in situ hybridization and immunohistochemistry (IHC) for researchers and drug development professionals.
RNAscope Pretreatment Optimization: A Complete Guide for Robust Spatial Gene Expression Analysis
This comprehensive guide provides researchers, scientists, and drug development professionals with essential knowledge and practical protocols for optimizing RNAscope tissue pretreatment.
High-Sensitivity In Situ Hybridization: Advanced Methods for Spatial Biology and Precision Research
This article provides a comprehensive overview of modern high-sensitivity in situ hybridization (ISH) methodologies, tailored for researchers and drug development professionals.
The RNAscope Hydrophobic Barrier Pen: A Critical Guide for Selection and Use in Research and Diagnostics
This article provides a comprehensive guide for researchers and drug development professionals on the selection and application of the hydrophobic barrier pen in RNAscope in situ hybridization assays.
RNAscope Technology: Principles, Applications, and Troubleshooting for Spatial Genomics
This article provides a comprehensive overview of the RNAscope in situ hybridization technology, a revolutionary spatial genomics platform.
Benchmarking Human Embryo Models: Validating Fidelity Against In Vivo References for Biomedical Research
This article provides a comprehensive framework for researchers and drug development professionals to authenticate stem cell-based human embryo models.